EMBO J. 1991 Sep;10(9):2661-8.

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.

Gotoh Y, Moriyama K, Matsuda S, Okumura E, Kishimoto T, Kawasaki H, Suzuki K, Yahara I, Sakai H, Nishida E.

Source

Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Japan.

Abstract

MAP kinase is activated and phosphorylated during M phase of the Xenopus oocyte cell cycle, and induces the interphase-M phase transition of microtubule dynamics in vitro. We have carried out molecular cloning of Xenopus M phase MAP kinase and report its entire amino acid sequence. There is no marked change in the MAP kinase mRNA level during the cell cycle. Moreover, studies with an anti-MAP kinase antiserum indicate that MAP kinase activity may be regulated posttranslationally, most likely by phosphorylation. We show that MAP kinase can be activated by microinjection of MPF into immature oocytes or by adding MPF to cell-free extracts of interphase eggs. These results suggest that MAP kinase functions as an intermediate between MPF and the interphase-M phase transition of microtubule organization.

PMID:: 1714387; [PubMed - indexed for MEDLINE]
PMCID:: PMC452967

Free PMC Article

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs. [EMBO J. 1993]
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs.
Nebreda AR, Hunt T. EMBO J. 1993 May; 12(5):1979-86.
Regulation of a major microtubule-associated protein by MPF and MAP kinase. [EMBO J. 1992]
Regulation of a major microtubule-associated protein by MPF and MAP kinase.
Shiina N, Moriguchi T, Ohta K, Gotoh Y, Nishida E. EMBO J. 1992 Nov; 11(11):3977-84.
An M-phase-specific protein kinase of Xenopus oocytes: partial purification and possible mechanism of its periodic activation. [Dev Biol. 1988]
An M-phase-specific protein kinase of Xenopus oocytes: partial purification and possible mechanism of its periodic activation.
Labbé JC, Picard A, Karsenti E, Dorée M. Dev Biol. 1988 May; 127(1):157-69.
Review Xenopus oocytes and the biochemistry of cell division. [Biochemistry. 1990]
Review Xenopus oocytes and the biochemistry of cell division.
Maller JL. Biochemistry. 1990 Apr 3; 29(13):3157-66.
Review M-phase-promoting factor activation. [J Cell Sci. 1992]
Review M-phase-promoting factor activation.
Meikrantz W, Schlegel RA. J Cell Sci. 1992 Mar; 101 ( Pt 3):475-81.

See reviews... See all...

Cited by 67 PubMed Central articles

MPF governs the assembly and contraction of actomyosin rings by activating RhoA and MAPK during chemical-induced cytokinesis of goat oocytes. [PLoS One. 2010]
MPF governs the assembly and contraction of actomyosin rings by activating RhoA and MAPK during chemical-induced cytokinesis of goat oocytes.
Wu YG, Zhou P, Lan GC, Gao D, Li Q, Wei DL, Wang HL, Tan JH. PLoS One. 2010 Sep 13; 5(9):e12706. Epub 2010 Sep 13.
Wounding Induces the Rapid and Transient Activation of a Specific MAP Kinase Pathway. [Plant Cell. 1997]
Wounding Induces the Rapid and Transient Activation of a Specific MAP Kinase Pathway.
Bogre L, Ligterink W, Meskiene I, Barker PJ, Heberle-Bors E, Huskisson NS, Hirt H. Plant Cell. 1997 Jan; 9(1):75-83.
A novel regulatory element determines the timing of Mos mRNA translation during Xenopus oocyte maturation. [EMBO J. 2002]
A novel regulatory element determines the timing of Mos mRNA translation during Xenopus oocyte maturation.
Charlesworth A, Ridge JA, King LA, MacNicol MC, MacNicol AM. EMBO J. 2002 Jun 3; 21(11):2798-806.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
Nucleotide
Primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.
Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.
EMBO J. 1991 Sep ;10(9):2661-8.

PubMed
Dependency and self-criticism: relationship with major depressive disorder, seve...
Dependency and self-criticism: relationship with major depressive disorder, severity of depression, and clinical presentation.
Depress Anxiety. 2007 ;24(8):586-96.

PubMed
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin,...
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs.
EMBO J. 1991 Sep ;10(9):2645-51.

PubMed
Comparative biological and clinical outcomes after a switch from a virologically...
Comparative biological and clinical outcomes after a switch from a virologically unsuccessful first protease inhibitor-containing antiretroviral combination to a 3-drug regimen containing efavirenz, nevirapine, or abacavir.
Clin Infect Dis. 2007 Jan 1 ;44(1):120-7. Epub 2006 Nov 16 .

PubMed
Trichomonas vaginalis infection in male sexual partners: implications for diagno...
Trichomonas vaginalis infection in male sexual partners: implications for diagnosis, treatment, and prevention.
Clin Infect Dis. 2007 Jan 1 ;44(1):13-22. Epub 2006 Nov 27 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.

Source

Abstract

MeSH Terms, Substances, Secondary Source ID

MeSH Terms

Substances

Secondary Source ID

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Cited by 67 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information