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Cell Metab. 2006 Dec;4(6):415-7.

Serotonin's SOS signal.

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  • 1Program in Gene Function and Expression and Program in Molecular Medicine, University of Massachusetts Medical School, Aaron Lazare Research Building Suite 615, 364 Plantation Street, Worcester, Massachusetts 01605, USA.


Neurotransmitters relay signals within the brain and to peripheral tissues, allowing communication between nerve cells. New work from in this issue of Cell Metabolism reveals that, in C. elegans, serotonin functions during conditions of stress through the well-characterized insulin/IGF-1 signaling pathway, suggesting a mechanism for the stress response.

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