Incontinence induces stratum corneum vulnerability and impairs the skin barrier function in the perianal region

Dermatology. 2006;213(4):293-9. doi: 10.1159/000096192.

Abstract

Background: Incontinence leads to a reduced skin barrier function, while also increasing the risk of skin breakdown.

Aim: To investigate the perianal skin barrier function of elderly patients with or without incontinence.

Methods: We compared the skin barrier function by investigating the skin hydration, the skin pH, the amount of ceramide and by making a dermatological skin inspection of the perianal region in patients with and without incontinence.

Results: Twenty-one incontinent patients (70.0%) showed a glossy skin, which indicates impairment of the skin barrier while none of the patients in the continence group did so. In the incontinence group, those who had a glossy skin showed a significantly greater skin pH and total amount of ceramide than those with a normal skin (p = 0.0099, p = 0.0179, respectively).

Conclusions: These results demonstrate that a glossy skin may be a useful indicator of a reduced perianal skin barrier function.

Publication types

  • Comparative Study

MeSH terms

  • Aged, 80 and over
  • Anal Canal
  • Body Water / chemistry
  • Ceramides / analysis
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hydrogen-Ion Concentration
  • Male
  • Perineum / pathology
  • Perineum / physiopathology*
  • Skin / chemistry
  • Skin / pathology
  • Skin Physiological Phenomena*
  • Urinary Incontinence / physiopathology*
  • Water Loss, Insensible / physiology

Substances

  • Ceramides