Cell. 2006 Dec 1;127(5):887-90.

Proteins kinases: chromatin-associated enzymes?

Source

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Abstract

Protein kinases contribute to the regulation of gene expression by interacting with transcription factors that are recruited to the regulatory regions of genes. Previous studies investigated the role of protein kinases in transcription initiation. Here, we discuss new insights gleaned from recent work showing that kinases can also interact with chromatin throughout the entire transcribed region of target genes (Pokholok et al., 2006; Proft et al., 2006).

PMID:: 17129776; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Review Visualizing chromatin dynamics in intact cells. [Biochim Biophys Acta. 2008]
Review Visualizing chromatin dynamics in intact cells.
Voss TC, Hager GL. Biochim Biophys Acta. 2008 Nov; 1783(11):2044-51. Epub 2008 Jul 16.
The Rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast. [J Biol Chem. 2008]
The Rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast.
Imbeault D, Gamar L, Rufiange A, Paquet E, Nourani A. J Biol Chem. 2008 Oct 10; 283(41):27350-4. Epub 2008 Aug 15.
Keys to open chromatin for transcription activation: FACT and Asf1. [Mol Cell. 2009]
Keys to open chromatin for transcription activation: FACT and Asf1.
Krebs A, Tora L. Mol Cell. 2009 May 14; 34(4):397-9.
The Sch9 kinase is a chromatin-associated transcriptional activator of osmostress-responsive genes. [EMBO J. 2007]
The Sch9 kinase is a chromatin-associated transcriptional activator of osmostress-responsive genes.
Pascual-Ahuir A, Proft M. EMBO J. 2007 Jul 11; 26(13):3098-108. Epub 2007 Jun 14.
Review Gene expression regulation and cancer. [Clin Transl Oncol. 2006]
Review Gene expression regulation and cancer.
Delgado MD, León J. Clin Transl Oncol. 2006 Nov; 8(11):780-7.

See reviews... See all...

Cited by 19 PubMed Central articles

Elongating under Stress. [Genet Res Int. 2011]
Elongating under Stress.
de Nadal E, Posas F. Genet Res Int. 2011; 2011:326286. Epub 2011 Sep 7.
Regulatory functions of SnRK1 in stress-responsive gene expression and in plant growth and development. [Plant Physiol. 2012]
Regulatory functions of SnRK1 in stress-responsive gene expression and in plant growth and development.
Cho YH, Hong JW, Kim EC, Yoo SD. Plant Physiol. 2012 Apr; 158(4):1955-64. Epub 2012 Jan 9.
Duplicity of protein kinase C-θ: Novel insights into human T-cell biology. [Transcription. 2011]
Duplicity of protein kinase C-θ: Novel insights into human T-cell biology.
Sutcliffe EL, Rao S. Transcription. 2011 Jul; 2(4):189-192.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Proteins kinases: chromatin-associated enzymes?
Proteins kinases: chromatin-associated enzymes?
Cell. 2006 Dec 1 ;127(5):887-90.

PubMed
Evaluation of aromatherapy in treating postoperative pain: pilot study.
Evaluation of aromatherapy in treating postoperative pain: pilot study.
Pain Pract. 2006 Dec ;6(4):273-7.

PubMed
Amnesia for electric dental pulp stimulation and picture recall test under diffe...
Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation.
Acta Anaesthesiol Scand. 2007 Jan ;51(1):16-21. Epub 2006 Nov 21 .

PubMed
The challenges of shift work.
The challenges of shift work.
Medsurg Nurs. 2006 Oct ;15(5):274-80.

PubMed
High school athletic departments as sentinel surveillance sites for community-as...
High school athletic departments as sentinel surveillance sites for community-associated methicillin-resistant staphylococcal infections.
Tex Med. 2006 Apr ;102(4):56-61.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: