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Nat Prod Rep. 2006 Dec;23(6):919-42. Epub 2006 Sep 18.

Birch bark research and development.

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  • 1University of Minnesota-Duluth, Natural Resources Research Institute, 5013 Miller Trunk Highway, Duluth, Minnesota 55811-1442, USA.


This review will detail progress made in the previous decade on the chemistry and bioactivity of birch bark extractive products. Current and future applications of birch bark natural products in pharmaceuticals, cosmetics, and dietary supplements for the prevention and treatment of cancer, HIV,and other human pathogens are reviewed. Current developments in the technology of birch bark processing are discussed. New approaches for the synthesis of potentially valuable birch bark triterpenoid derivatives are also reviewed.

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