Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity

Cell Res. 2006 Dec;16(12):961-3. doi: 10.1038/sj.cr.7310112.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Caspase Inhibitors*
  • Caspases / metabolism*
  • Drug Design*
  • Enzyme Inhibitors / chemical synthesis*
  • Humans
  • Substrate Specificity

Substances

  • Caspase Inhibitors
  • Enzyme Inhibitors
  • Caspases