Antimicrob Agents Chemother. 2007 Feb;51(2):777-82. Epub 2006 Nov 20.

First characterization of fluoroquinolone resistance in Streptococcus suis.

Escudero JA, San Millan A, Catalan A, de la Campa AG, Rivero E, Lopez G, Dominguez L, Moreno MA, Gonzalez-Zorn B.

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Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain.

Abstract

We have identified and sequenced the genes encoding the quinolone-resistance determining region (QRDR) of ParC and GyrA in fluoroquinolone-susceptible and -resistant Streptococcus suis clinical isolates. Resistance is the consequence of single point mutations in the QRDRs of ParC and GyrA and is not due to clonal spread of resistant strains or horizontal gene transfer with other bacteria.

PMID:: 17116660; [PubMed - indexed for MEDLINE]
PMCID:: PMC1797769

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GENBANK/DQ832724
GENBANK/DQ832725
GENBANK/DQ832726
GENBANK/DQ832727
GENBANK/DQ832728
GENBANK/DQ832729
GENBANK/DQ832730
GENBANK/DQ832731
GENBANK/DQ832732
GENBANK/DQ832733
GENBANK/DQ832734
GENBANK/DQ832735
GENBANK/DQ832736
GENBANK/DQ832737
GENBANK/DQ832738
GENBANK/DQ832739
GENBANK/DQ832740
GENBANK/DQ832741
GENBANK/DQ832742
GENBANK/DQ832743
GENBANK/DQ832744
GENBANK/DQ832745
GENBANK/DQ832746
GENBANK/DQ832747
GENBANK/DQ832748
GENBANK/DQ832749
GENBANK/DQ832750
GENBANK/DQ832751
GENBANK/DQ832752
GENBANK/DQ832753
GENBANK/DQ832754
GENBANK/DQ832755
GENBANK/DQ832756
GENBANK/DQ832757
GENBANK/DQ832758
GENBANK/DQ832759

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Cited by 6 PubMed Central articles

Molecular Dynamics Simulation of the Complex PBP-2x with Drug Cefuroxime to Explore the Drug Resistance Mechanism of Streptococcus suis R61. [PLoS One. 2012]
Molecular Dynamics Simulation of the Complex PBP-2x with Drug Cefuroxime to Explore the Drug Resistance Mechanism of Streptococcus suis R61.
Ge Y, Wu J, Xia Y, Yang M, Xiao J, Yu J. PLoS One. 2012; 7(4):e35941. Epub 2012 Apr 26.
Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. [Front Microbiol. 2011]
Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen.
Palmieri C, Varaldo PE, Facinelli B. Front Microbiol. 2011; 2:235. Epub 2011 Nov 25.
Comparative genomics study of multi-drug-resistance mechanisms in the antibiotic-resistant Streptococcus suis R61 strain. [PLoS One. 2011]
Comparative genomics study of multi-drug-resistance mechanisms in the antibiotic-resistant Streptococcus suis R61 strain.
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