E-medicine covers the whole range of medical process and service. Multi-agent approach is suitable for the development of e-medicine systems. In this paper, firstly the requirements of e-medicine are analyzed and taxonomy is proposed for e-medicine systems. Secondly multi-agent approach is introduced for developing e-medicine systems, and the design of agents and the design of multi-agent structure are presented for e-medicine systems. Finally a case study is presented on a telemedicine for diabetes to illustrate the development of e-medicine systems. Then, our future work is to implement the proposed system.