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J Bacteriol. 1991 Jun;173(11):3605-8.

Further characterizations of bleomycin-sensitive (blm) mutants of Saccharomyces cerevisiae with implications for a radiomimetic model.

Author information

  • City University of New York, Department of Microbiology, Medical School, New York 10031.

Abstract

Direct selection for 12 mutations (blm) conferring hypersensitivities to lethal effects of bleomycins in Saccharomyces cerevisiae resulted in mutants exhibiting cross-hypersensitivity to ionizing radiation and hydrogen peroxide. Remaining mutations did not confer cross-hypersensitivity to radiation. All blm mutations were recessive, except codominant blm3-1, and were assigned to seven complementation groups.

PMID:
1710619
[PubMed - indexed for MEDLINE]
PMCID:
PMC207981
Free PMC Article
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