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Genome Biol. 2006;7(11):R106.

Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas.

Author information

  • 1Institute for Systems Biology, N 34th Street, Seattle, WA 98103, USA. nking@systemsbiology.org

Abstract

We present the Saccharomyces cerevisiae PeptideAtlas composed from 47 diverse experiments and 4.9 million tandem mass spectra. The observed peptides align to 61% of Saccharomyces Genome Database (SGD) open reading frames (ORFs), 49% of the uncharacterized SGD ORFs, 54% of S. cerevisiae ORFs with a Gene Ontology annotation of 'molecular function unknown', and 76% of ORFs with Gene names. We highlight the use of this resource for data mining, construction of high quality lists for targeted proteomics, validation of proteins, and software development.

PMID:
17101051
[PubMed - indexed for MEDLINE]
PMCID:
PMC1794584
Free PMC Article

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