Trends Parasitol. 2007 Jan;23(1):14-20. Epub 2006 Nov 13.

'Oming in on schistosomes: prospects and limitations for post-genomics.

Wilson RA, Ashton PD, Braschi S, Dillon GP, Berriman M, Ivens A.

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Department of Biology, University of York, PO Box 373, York YO10 5YW, UK. raw3@york.ac.uk

Abstract

The recent release of version 3 of the Schistosoma mansoni genome assembly has made a wealth of information available to researchers. Here, progress made in schistosome genomics and post-genomics is considered. The current status of knowledge about the genome, transcriptome, proteome, glycome and immunome is summarized and recent publications briefly reviewed. The prospects for advances in understanding schistosome biology are highlighted. Most importantly, the limitations (which are mostly technical) that need to be addressed before the full potential of the genome database(s) can be realized are emphasized.

PMID:: 17097923; [PubMed - indexed for MEDLINE]

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