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    J Heart Lung Transplant. 2006 Nov;25(11):1376-9. Epub 2006 Oct 11.

    Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia.

    Source

    Department of Cardiology, Children's Hospital, Boston, Massachusetts 02215, USA. christopher.almond@childrens.harvard.edu <christopher.almond@childrens.harvard.edu>

    Abstract

    Bivalirudin, a direct thrombin inhibitor, has recently emerged as a promising option for anti-coagulation during cardiopulmonary bypass in patients who cannot receive heparin. There is limited experience with the use of bivalirudin in children. We present the case of a child with heparin-induced thrombocytopenia with thrombosis (HIT Type II) who underwent successful orthotopic cardiac transplantation using bivalirudin as the primary anti-coagulant for cardiopulmonary bypass.

    PMID:
    17097505
    [PubMed - indexed for MEDLINE]

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