A preliminary investigation of ADHD symptoms in persons with celiac disease

J Atten Disord. 2006 Nov;10(2):200-4. doi: 10.1177/1087054706292109.

Abstract

Objective: Several studies report a possible association of celiac disease (CD) with psychiatric and psychological disturbances, such as ADHD.

Method: The authors assess 132 participants from 3 to 57 years of age (M = 19.3 years) affected by CD for the possibility of an associated ADHD-like symptomatology, using the Conner Scale Hypescheme, a behavioral scale similar to the Conners Rating Scales, before their gluten-free diet was started and 6 months later.

Results: The overall score improves significantly as well as most of the ADHD-like symptomatology specific features (Bonferroni-corrected, paired-sample t tests).

Conclusion: The data indicate that ADHD-like symptomatology is markedly overrepresented among untreated CD patients and that a gluten-free diet may improve symptoms significantly within a short period of time. The results of this study also suggest that CD should be included in the list of diseases associated with ADHD-like symptomatology.

MeSH terms

  • Adolescent
  • Adult
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / diet therapy
  • Attention Deficit Disorder with Hyperactivity / epidemiology*
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Celiac Disease / diagnosis
  • Celiac Disease / diet therapy
  • Celiac Disease / epidemiology*
  • Celiac Disease / psychology
  • Child
  • Child, Preschool
  • Comorbidity
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Glutens / administration & dosage
  • Humans
  • Male
  • Middle Aged

Substances

  • Glutens