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J Bacteriol. 2007 Jan;189(1):280-3. Epub 2006 Nov 3.

Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus.

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  • 1Microbial Genetics, University of Tübingen, 72076 Tübingen, Germany.


Staphylococcus aureus peptidoglycan (PG) is completely resistant to the hydrolytic activity of lysozyme. Here we show that modifications in PG by O acetylation, wall teichoic acid, and a high degree of cross-linking contribute to this resistance.

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