Glucose sparing in peritoneal dialysis: implicatio...[Kidney Int Suppl. 2006]

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1: Kidney Int Suppl. 2006 Nov;(103):S104-9.Links

Glucose sparing in peritoneal dialysis: implications and metrics.

Holmes C, Mujais S.

Renal Division, Baxter Healthcare Corporation, McGaw Park, IL 60085-9815, USA.

Glucose sparing is a central component of modern peritoneal dialysis therapy, necessary to reduce the trade-offs of the therapy in terms of membrane protection and alleviation of systemic consequences. We present a detailed exploration of a metric for this approach in the form of the index of ultrafiltration efficiency, that we propose as a guide for designing therapeutic regimens and for the development of new dialysis solutions. Based on insights from exploration of ultrafiltration efficiency with various dialysis solutions, we propose an approach to optimizing dialysis prescription.

PMID: 17080098 [PubMed - indexed for MEDLINE]

Development of a computer-aided diagnosis system for a new modality of renal replacement therapy: an integrated approach combining both peritoneal dialysis and hemodialysis. [Comput Biol Med. 2005]
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An exploratory study of a novel peritoneal combination dialysate (1.36% glucose/7.5% icodextrin), demonstrating improved ultrafiltration compared to either component studied alone. [Perit Dial Int. 2003]
Clinical biocompatibility of a neutral peritoneal dialysis solution with minimal glucose-degradation products--a 1-year randomized control trial. [Nephrol Dial Transplant. 2007]
ReviewEstimates of peritoneal membrane function--new insights. [Nephrol Dial Transplant. 2006]

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Glucose sparing in peritoneal dialysis: implications and metrics.

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