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Cornea. 2006 Jul;25(6):750-6.

Corneal topographic features in a family with nanophthalmos.

Author information

  • 1Department of Ophthalmology, Aintree University Hospitals, Liverpool, United Kingdom. sathish.srinivasan@gmail.com

Abstract

PURPOSE:

To characterize the corneal topographic features in a family with nanophthalmos.

METHODS:

Two observational case reports and a review of the literature. Corneal shape was analyzed using a topographic modeling system (TMS) and an Orbscan topographic system, with further analysis based on Fourier series and Zernicke polynomials. A control group was used for comparison.

RESULTS:

Two female family members with nanophthalmos belonging to the same generation showed significant irregular corneal astigmatism and corneal steepening.

CONCLUSION:

Topographic corneal steepening and irregular astigmatism seems to be associated in 1 family with inherited nanophthalmos. Higher degrees of irregular astigmatism, which were not evident without a topographic analysis, may account, in part, for the unexplained visual reduction.

PMID:
17077675
[PubMed - indexed for MEDLINE]
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