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Genome Biol. 2006;7(10):237. Epub 2006 Oct 24.

Leaner and meaner genomes in Escherichia coli.

Author information

  • Center for Biological Sequence Analysis, BioCentrum-DTU, Technical University of Denmark, DK-2800 Kgs, Lyngby, Denmark. dave@cbs.dtu.dk

Abstract

A 'better' Escherichia coli K-12 genome has recently been engineered in which about 15% of the genome has been removed by planned deletions. Comparison with related bacterial genomes that have undergone a natural reduction in size suggests that there is plenty of scope for yet more deletions.

PMID:
17076878
[PubMed - indexed for MEDLINE]
PMCID:
PMC1794563
Free PMC Article

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