Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
CMAJ. 2006 Oct 24;175(9):1087-92.

Diagnosis and treatment of deep-vein thrombosis.

Author information

  • 1Department of Medicine, Division of Hematology, and the Ottawa Health Research Institute, University of Ottawa, Ottawa, Ont. dscarvelis@ottawahospital.on.ca

Erratum in

  • CMAJ. 2007 Nov 20;177(11):1392.

Abstract

Deep-vein thrombosis (DVT) is a common condition that can lead to complications such as postphlebitic syndrome, pulmonary embolism and death. The approach to the diagnosis of DVT has evolved over the years. Currently an algorithm strategy combining pretest probability, D-dimer testing and compression ultrasound imaging allows for safe and convenient investigation of suspected lower-extremity thrombosis. Patients with low pretest probability and a negative D-dimer test result can have proximal DVT excluded without the need for diagnostic imaging. The mainstay of treatment of DVT is anticoagulation therapy, whereas interventions such as thrombolysis and placement of inferior vena cava filters are reserved for special situations. The use of low-molecular-weight heparin allows for outpatient management of most patients with DVT. The duration of anticoagulation therapy depends on whether the primary event was idiopathic or secondary to a transient risk factor. More research is required to optimally define the factors that predict an increased risk of recurrent DVT to determine which patients can benefit from extended anticoagulant therapy.

PMID:
17060659
[PubMed - indexed for MEDLINE]
PMCID:
PMC1609160
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk