Int J Legal Med. 2007 Mar;121(2):124-7. Epub 2006 Oct 21.

Variation of 52 new Y-STR loci in the Y Chromosome Consortium worldwide panel of 76 diverse individuals.

Lim SK, Xue Y, Parkin EJ, Tyler-Smith C.

Source

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

Abstract

We have established 16 small multiplex reactions of two-four loci to amplify 52 recently described single-copy simple Y-STRs and typed these loci in a worldwide panel of 74 diverse men and two women. Two Y-STRs were found to be commonly multicopy in this sample set and were excluded from the study. Of the remaining 50, four (DYS481, DYS570, DYS576 and DYS643) showed higher diversities than the commonly used loci and can potentially provide increased haplotype discrimination in both forensic and anthropological work. Ten loci showed occasional missing alleles, duplicated peaks or intermediate-sized alleles.

PMID:: 17058101; [PubMed - indexed for MEDLINE]
PMCID:: PMC1794629

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Wellcome Trust/United Kingdom

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