Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nat Rev Mol Cell Biol. 2006 Nov;7(11):820-8.

Data-driven modelling of signal-transduction networks.

Author information

  • 1Cell Decision Processes Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Abstract

New technologies are permitting large-scale quantitative studies of signal-transduction networks. Such data are hard to understand completely by inspection and intuition. 'Data-driven models' help users to analyse large data sets by simplifying the measurements themselves. Data-driven modelling approaches such as clustering, principal components analysis and partial least squares can derive biological insights from large-scale experiments. These models are emerging as standard tools for systems-level research in signalling networks.

PMID:
17057752
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk