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1: J Vasc Interv Radiol. 2006 Oct;17(10):1693-5.Click here to read Links
Comment in:
J Vasc Interv Radiol. 2007 Jul;18(7):937; author reply 937-8.

Bradyarrhythmias during use of the AngioJet system.

Dwarka D, Schwartz SA, Smyth SH, O'Brien MJ.

Department of Radiology, University of Arizona Health Sciences Center, 1501 North Campbell Avenue, Tucson, AZ 85724-5067, USA.

The AngioJet system is an effective thrombectomy device, but it may cause chest discomfort and provoke bradyarrhythmias that range from mild bradycardia to asystole. The cause of AngioJet-induced bradyarrhythmia is unknown, although several hypotheses have attempted to explain the phenomenon. Herein several cases will be described, followed by a review of the relevant literature. The literature review suggests that the cause may be related to the effects of the hydrodynamic jets on stretch-activated receptors present on the vascular endothelium, and that pretreatment with gadolinium or streptomycin might prevent activation of these receptors.

PMID: 17057013 [PubMed - indexed for MEDLINE]