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Nature. 2006 Oct 19;443(7113):796-802.

Cell death in the nervous system.

Author information

  • 1Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, California 94945, USA. dbredesen@buckinstitute.org

Abstract

Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease trigger neuronal cell death through endogenous suicide pathways. Surprisingly, although the cell death itself may occur relatively late in the course of the degenerative process, the mediators of the underlying cell-death pathways have shown promise as potential therapeutic targets.

PMID:
17051206
[PubMed - indexed for MEDLINE]
PMCID:
PMC3970704
Free PMC Article
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