Immunity. 2006 Oct;25(4):523-5.

Exiting the outside world for cross-presentation.

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Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

Abstract

How are extracellular proteins cross-presented on MHC class I molecules? In this issue of Immunity, demonstrate that the ER-associated degradation (ERAD) export pathway operates in the phagosomes of dendritic cells and transfers antigens into the MHC class I pathway.

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A role for the endoplasmic reticulum protein retrotranslocation machinery during crosspresentation by dendritic cells. [Immunity. 2006]
A role for the endoplasmic reticulum protein retrotranslocation machinery during crosspresentation by dendritic cells.Ackerman AL, Giodini A, Cresswell P. Immunity. 2006 Oct; 25(4):607-17. Epub 2006 Oct 5.

PMID:: 17046678; [PubMed - indexed for MEDLINE]

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ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. [Nature. 2003]
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