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J Membr Biol. 2006;211(2):65-79. Epub 2006 Oct 14.

COPI-mediated transport.

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  • 1Biochemie Zentrum, University of Heidelberg, Im Neuenheimer Feld 328, D-69120, Heidelberg, Germany.


COPI-coated vesicles are protein and liquid carriers that mediate transport within the early secretory pathway. In this Topical Review, we present their main protein components and discuss current models for cargo sorting. Finally, we describe the striking similarities that exist between the COPI system and the two other characterized types of vesicular carriers: COPII- and clathrin-coated vesicles.

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