Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Mol Psychiatry. 2007 Jan;12(1):2-22. Epub 2006 Oct 10.

The genetics of autistic disorders and its clinical relevance: a review of the literature.

Author information

  • Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany. christine.freitag@uniklinikum-saarland.de

Abstract

Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially delineate the phenotype of AD and discuss aspects of differential diagnosis, which are particularly relevant with regard to the genetics of autism. Cytogenetic and molecular genetic studies will be presented in detail, and the possibly involved aetiopathological pathways will be described. Implications of the different genetic findings for genetic counselling will be mentioned.

PMID:
17033636
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk