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An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
J Biol Chem. 2006 Dec 8;281(49):37668-74. doi: 10.1074/jbc.M605186200. Epub 2006 Oct 6.
J Biol Chem. 2006.
PMID: 17028192
Free article.
Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.
Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.
Johnson D, et al.
Diabetes. 2007 Jun;56(6):1694-702. doi: 10.2337/db07-0026. Epub 2007 Mar 14.
Diabetes. 2007.
PMID: 17360975
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