Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Eur Radiol. 2007 Mar;17(3):743-61. Epub 2006 Sep 21.

MR imaging of therapy-induced changes of bone marrow.

Author information

  • 1Department of Radiology, University of California San Francisco, 505 Parnassus Ave., San Francisco, CA, 94143-0628, USA. daldrup@radiology.ucsf.edu

Abstract

MR imaging of bone marrow infiltration by hematologic malignancies provides non-invasive assays of bone marrow cellularity and vascularity to supplement the information provided by bone marrow biopsies. This article will review the MR imaging findings of bone marrow infiltration by hematologic malignancies with special focus on treatment effects. MR imaging findings of the bone marrow after radiation therapy and chemotherapy will be described. In addition, changes in bone marrow microcirculation and metabolism after anti-angiogenesis treatment will be reviewed. Finally, new specific imaging techniques for the depiction of regulatory events that control blood vessel growth and cell proliferation will be discussed. Future developments are directed to yield comprehensive information about bone marrow structure, function and microenvironment.

Comment in

PMID:
17021706
[PubMed - indexed for MEDLINE]
PMCID:
PMC1797072
Free PMC Article

Images from this publication.See all images (12)Free text

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Springer Icon for PubMed Central
    Loading ...
    Write to the Help Desk