Send to:

Choose Destination
See comment in PubMed Commons below
Cell. 2006 Oct 6;127(1):40-2.

Unwinding a path to nuclear beta-catenin.

Author information

  • 1Program of Neurobiology, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 USA.


In this issue of Cell, Yang et al. (2006b) show that PDGF, a growth factor that induces the transition of epithelial cells to mesenchymal cells, stimulates the c-Abl kinase-dependent phosphorylation of p68 RNA helicase. Phosphorylated p68 dissociates beta-catenin from the Axin destruction complex, thereby promoting nuclear beta-catenin signaling independent of Wnt activation.

[PubMed - indexed for MEDLINE]
Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk