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Nat Rev Drug Discov. 2006 Oct;5(10):821-34.

Drugs, their targets and the nature and number of drug targets.

Author information

  • 1Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, 06120 Halle, Germany.

Erratum in

  • Nat Rev Drug Discov. 2007 Feb;6(2):126.


What is a drug target? And how many such targets are there? Here, we consider the nature of drug targets, and by classifying known drug substances on the basis of the discussed principles we provide an estimation of the total number of current drug targets.

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