Abstract
A single dose of 6 Gy irradiation significantly reduced the total WBC count while in herbal formulation (AC II) treated groups it was found to be significantly increased. Similarly bone marrow cellularity and alpha-esterase positive cells, which were lowered by radiation, were partly restored in AC II treated groups. The data indicate that AC II can overcome the immunosuppression produced by irradiation.
MeSH terms
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Adjuvants, Immunologic / administration & dosage
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Adjuvants, Immunologic / therapeutic use*
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Administration, Oral
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Animals
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Antibody Formation / drug effects
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Antibody Formation / radiation effects
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Body Weight / drug effects
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Body Weight / radiation effects
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Bone Marrow Cells / cytology
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Bone Marrow Cells / drug effects
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Bone Marrow Cells / radiation effects
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Esterases / metabolism
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Gamma Rays*
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Hemolytic Plaque Technique
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Immune Tolerance* / drug effects
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Immune Tolerance* / radiation effects
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Medicine, Ayurvedic*
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Mice
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Mice, Inbred BALB C
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Plant Preparations / administration & dosage
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Plant Preparations / therapeutic use*
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Radiation Injuries, Experimental / drug therapy*
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Radiation Injuries, Experimental / immunology
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Spleen / cytology
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Spleen / drug effects
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Spleen / radiation effects
Substances
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AC II herbal formulation
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Adjuvants, Immunologic
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Plant Preparations
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Esterases