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Cell. 2006 Sep 22;126(6):1025-8.

The first high-resolution DNA "methylome".

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  • 1Institute of Plant Biology and Zürich-Basel Plant Science Center, University of Zürich, Zollikerstrasse 107, CH-8008 Zürich, Switzerland. hampe@botinst.unizh.ch <hampe@botinst.unizh.ch>


Cytosine methylation plays a crucial role in the regulation of gene expression and the control of genome stability in higher eukaryotes. Despite its importance for normal development, the degree and genome-wide distribution of DNA methylation has remained largely unknown. In this issue of Cell, fill this gap by presenting a high-resolution map of DNA methylation in the genome of the flowering plant Arabidopsis.

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