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Brain Lang. 2007 Jul;102(1):114-25. Epub 2006 Sep 18.

Pharmacotherapy of aphasia: myth or reality?

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  • 1INSERM U455, CHU Purpan, Toulouse 31059, France.


Pharmacotherapy of aphasia had been discussed for the last twenty years with first bromocriptine and amphetamine and then serotoninergic, GABAergic and cholinergic agents. Here, we reviewed the MEDLINE available reports of drug therapy for aphasia. So far, proofs of efficiency were found indubitable for none of the studied molecules. However, some of them showed limited efficiency (piracetam and amphetamine). Moreover, drug therapies for aphasia were less efficient alone than when they were associated with speech therapy.

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