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Cell Cycle. 2006 Sep;5(18):2057-9. Epub 2006 Sep 15.

New insights regarding vessel regression.

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  • 1Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA.


The regression of blood vessels is an intrinsic feature of both physiological and pathological processes. This suggests the existence of molecular regulators of regression, which would be potential targets for management and therapy of numerous diseases involving angiogenesis. This review summarizes some of the prevailing views on vessel regression and highlights our recent contribution to the field.

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