Vaccine. 2006 Aug 31;24 Suppl 3:S3/233-41.

Chapter 28: Studies to assess the long-term efficacy and effectiveness of HPV vaccination in developed and developing countries.

Lehtinen M, Herrero R, Mayaud P, Barnabas R, Dillner J, Paavonen J, Smith PG.

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National Public Health Institute, Department of Infectious Disease Epidemiology, KTL, Oulu, Finland. Matti.Lehtinen@uta.fi

Abstract

We review studies of the implementation of human papillomavirus (HPV) vaccination programmes in developed and developing countries. The review spans the period from establishment of long-term vaccine efficacy follow-up studies, operational research on issues of vaccine preparedness, and relevant predictive modelling studies during the pre-licensure phase to plans of phase IV effectiveness trials, forms of epidemiological surveillance, and further operational research in the post-licensure phase. Much of the research is already ongoing. Depending on the results of the planned immuno bridging studies among HIV-negative and HIV-positive women, further phase III and/or phase IV trials may be warranted.

PMID:: 16950012; [PubMed - indexed for MEDLINE]

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Papillomavirus Vaccines

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