Clinical Trial Service Unit & Epidemiological Studies Unit, Richard Doll Building, University of Oxford, Old Road Campus, Oxford, UK. max.parkin@ctsu.ox.ac.uk
On the basis of current evidence regarding human papillomavirus (HPV) and cancer, this chapter provides estimates of the global burden of HPV-related cancers, and the proportion that are actually "caused" by infection with HPV types, and therefore potentially preventable. We also present trends in incidence and mortality of these cancers in the past, and consider their likely future evolution.