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Genome Biol. 2006;7(8):230.

Unraveling the transcriptional network controlling ES cell pluripotency.

Author information

  • 1Division of Hematology-Oncology, Children's Hospital and the Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Embryonic stem cells (ES cells) are powerful tools for genetic engineering and hold significant potential for regenerative medicine. Recent work provides new insights into ES cell pluripotency and delineates separate transcriptional pathways in ES cells for maintenance of the undifferentiated state and for self-renewal.

PMID:
16942632
[PubMed - indexed for MEDLINE]
PMCID:
PMC1779601
Free PMC Article

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