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1: Genome Biol. 2006;7(8):230.Click here to read Click here to read Links

Unraveling the transcriptional network controlling ES cell pluripotency.

Rao S, Orkin SH.

Division of Hematology-Oncology, Children's Hospital and the Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

Embryonic stem cells (ES cells) are powerful tools for genetic engineering and hold significant potential for regenerative medicine. Recent work provides new insights into ES cell pluripotency and delineates separate transcriptional pathways in ES cells for maintenance of the undifferentiated state and for self-renewal.

PMID: 16942632 [PubMed - indexed for MEDLINE]

PMCID: PMC1779601