Clin Infect Dis. 2006 Oct 1;43(7):939-41. Epub 2006 Aug 23.

Less than 95% adherence to nonnucleoside reverse-transcriptase inhibitor therapy can lead to viral suppression.

Source

Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, and the Positive Health Program, San Francisco General Hospital, University of California, San Francisco, CA 94143-1372, USA. db@epi-center.ucsf.edu

Abstract

For antiretroviral therapy, the 95% adherence "threshold" is based on nucloside-exposed patients who are receiving partially suppressive, unboosted protease inhibitor regimens. Using unannounced pill counts and electronic medication monitoring, viral suppression is common with a 54%-100% mean adherence level to nonnucleoside reverse-transcriptase-inhibitor regimens. Although perfect adherence is an important goal, viral suppression is possible with moderate adherence to potent regimens.

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Clin Infect Dis. 2006 Oct 1;43(7):942-4.

PMID:: 16941380; [PubMed - indexed for MEDLINE]

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