The elusive yeast interactome. [Genome Biol. 2006]

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1: Genome Biol. 2006;7(6):223. Links

The elusive yeast interactome.

Goll J, Uetz P.

Institut für Genetik, Forschungszentrum Karlsruhe, Box 3640, 76021 Karlsruhe, Germany.

Simple eukaryotic cells such as yeast could contain around 800 protein complexes, as two new comprehensive studies show. But slightly different approaches resulted in surprising differences between the two datasets, showing that more work is required to get a complete picture of the yeast interactome.

PMID: 16938899 [PubMed - indexed for MEDLINE]

PMCID: PMC1779532

High-quality binary protein interaction map of the yeast interactome network.
Science. 2008 Oct 3; 322(5898):104-10. Epub 2008 Aug 21.

[Science. 2008]
Proteomics in a small world.
Nat Struct Biol. 2002 Mar; 9(3):153.

[Nat Struct Biol. 2002]
On the number of protein-protein interactions in the yeast proteome.
Nucleic Acids Res. 2003 Jul 15; 31(14):4157-61.

[Nucleic Acids Res. 2003]
ReviewYeast two-hybrid contributions to interactome mapping.
Curr Opin Biotechnol. 2006 Aug; 17(4):387-93. Epub 2006 Jun 27.

[Curr Opin Biotechnol. 2006]
ReviewCapturing cellular machines by systematic screens of protein complexes.
Trends Microbiol. 2006 Aug; 14(8):336-9. Epub 2006 Jun 16.

[Trends Microbiol. 2006]
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Cited by 9 PubMed Central articles

Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.
Shevchenko A, Roguev A, Schaft D, Buchanan L, Habermann B, Sakalar C, Thomas H, Krogan NJ, Shevchenko A, Stewart AF. Genome Biol. 2008; 9(11):R167. Epub 2008 Nov 28.

[Genome Biol. 2008]
High throughput protein-protein interaction data: clues for the architecture of protein complexes.
Krycer JR, Pang CN, Wilkins MR. Proteome Sci. 2008 Nov 26; 6:32. Epub 2008 Nov 26.

[Proteome Sci. 2008]
Global investigation of protein-protein interactions in yeast Saccharomyces cerevisiae using re-occurring short polypeptide sequences.
Pitre S, North C, Alamgir M, Jessulat M, Chan A, Luo X, Green JR, Dumontier M, Dehne F, Golshani A. Nucleic Acids Res. 2008 Aug; 36(13):4286-94. Epub 2008 Jun 27.

[Nucleic Acids Res. 2008]
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