Nat Clin Pract Neurol. 2006 Jun;2(6):310-20.

Surgery insight: Deep brain stimulation for movement disorders.

Source

Johns Hopkins University School of Medicine, Baltimore, MA 21287, USA.

Abstract

Over the past two decades, deep brain stimulation (DBS) has supplanted lesioning techniques for the treatment of movement disorders, and has been shown to be safe and efficacious. The primary therapeutic indications for DBS are essential tremor, dystonia and Parkinson's disease. In the case of Parkinson's disease, DBS is effective for treating the primary symptoms--tremor, bradykinesia and rigidity--as well as the motor complications of drug treatment. Progress has been made in understanding the effects of stimulation at the neuronal level, and this knowledge should eventually improve the effectiveness of this therapy. Preliminary studies also indicate that DBS might be used to treat Tourette's syndrome, obsessive-compulsive disorder, depression and epilepsy. As we will discuss in this review, the success of DBS depends on an appropriate rationale for the procedure, and on collaborations between neurologists and neurosurgeons in defining outcomes.

PMID:: 16932575; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Supplemental Content

Save items

Related citations in PubMed

Reoperation for suboptimal outcomes after deep brain stimulation surgery. [Neurosurgery. 2008]
Reoperation for suboptimal outcomes after deep brain stimulation surgery.
Ellis TM, Foote KD, Fernandez HH, Sudhyadhom A, Rodriguez RL, Zeilman P, Jacobson CE 4th, Okun MS. Neurosurgery. 2008 Oct; 63(4):754-60; discussion 760-1.
Review The treatment of movement disorders by deep brain stimulation. [Neurotherapeutics. 2008]
Review The treatment of movement disorders by deep brain stimulation.
Yu H, Neimat JS. Neurotherapeutics. 2008 Jan; 5(1):26-36.
Review Deep brain stimulation: current and emerging indications. [Mo Med. 2008]
Review Deep brain stimulation: current and emerging indications.
Dowling J. Mo Med. 2008 Sep-Oct; 105(5):424-8.
Management of referred deep brain stimulation failures: a retrospective analysis from 2 movement disorders centers. [Arch Neurol. 2005]
Management of referred deep brain stimulation failures: a retrospective analysis from 2 movement disorders centers.
Okun MS, Tagliati M, Pourfar M, Fernandez HH, Rodriguez RL, Alterman RL, Foote KD. Arch Neurol. 2005 Aug; 62(8):1250-5. Epub 2005 Jun 13.
Review Deep brain stimulation in movement disorders. [Semin Neurol. 2007]
Review Deep brain stimulation in movement disorders.
Uc EY, Follett KA. Semin Neurol. 2007 Apr; 27(2):170-82.

See reviews... See all...

Cited by 3 PubMed Central articles

Studies of properties of "Pain Networks" as predictors of targets of stimulation for treatment of pain. [Front Integr Neurosci. 2011]
Studies of properties of "Pain Networks" as predictors of targets of stimulation for treatment of pain.
Liu CC, Franaszczuk P, Crone NE, Jouny C, Lenz FA. Front Integr Neurosci. 2011; 5:80. Epub 2011 Dec 5.
Review Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies. [Parkinsonism Relat Disord. 2010]
Review Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies.
Morishita T, Foote KD, Burdick AP, Katayama Y, Yamamoto T, Frucht SJ, Okun MS. Parkinsonism Relat Disord. 2010 Mar; 16(3):153-62. Epub 2009 Nov 5.
Selective extracellular stimulation of individual neurons in ganglia. [J Neural Eng. 2008]
Selective extracellular stimulation of individual neurons in ganglia.
Lu H, Chestek CA, Shaw KM, Chiel HJ. J Neural Eng. 2008 Sep; 5(3):287-309. Epub 2008 Aug 19.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Surgery insight: Deep brain stimulation for movement disorders.
Surgery insight: Deep brain stimulation for movement disorders.
Nat Clin Pract Neurol. 2006 Jun ;2(6):310-20.

PubMed
How strong is the evidence for the efficacies of different drug treatments for n...
How strong is the evidence for the efficacies of different drug treatments for neuropathic pain?
Nat Clin Pract Neurol. 2006 Apr ;2(4):186-7.

PubMed
Comparative analysis of the retroviral pol and env protein sequences reveal diff...
Comparative analysis of the retroviral pol and env protein sequences reveal different evolutionary trees.
Virus Genes. 1990 Feb ;3(3):195-204.

PubMed
Can vaccinating older adults against varicella zoster virus prevent herpes zoste...
Can vaccinating older adults against varicella zoster virus prevent herpes zoster and postherpetic neuralgia?
Nat Clin Pract Neurol. 2005 Nov ;1(1):18-9.

PubMed
Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemi...
Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome.
Nat Clin Pract Nephrol. 2005 Dec ;1(2):80-6.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: