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    Langenbecks Arch Surg. 2006 Sep;391(5):495-8. Epub 2006 Aug 19.

    Future perspectives and research initiatives in fast-track surgery.

    Source

    Section for Surgical Pathophysiology, the Juliane Marie Centre, 4074, Rigshospitalet, 2100 Copenhagen, Denmark. henrik.kehlet@rh.dk

    Abstract

    BACKGROUND AND AIMS:

    Major surgery is still followed by a risk of morbidity, a need for hospitalisation and convalescence. Fast-track surgery has been introduced as a coordinated effort to combine unimodal evidence-based principles of care into a multi-modal effort to enhance recovery. The aim of this article was to update recent data on fast-track abdominal surgery and outline future strategies for research.

    RESULTS:

    The data from fast-track colonic resection support the validity of the concept because pain, ileus, cardiopulmonary function and muscle function were all improved, compared with traditional treatment and with reduced post-operative fatigue and convalescence. Although less data is available, similar positive results may be achieved in other types of major surgery. Current research initiatives include improved multi-modal non-opioid analgesia, rational principles for perioperative fluid management, pharmacological reduction of surgical stress responses and the role of laparoscopic procedures within the fast-track concept.

    CONCLUSIONS:

    Fast-track surgery has evolved as a valid concept to improve post-operative outcome. Further progress may be expected based upon intensified research within perioperative pathophysiology and a multi-disciplinary collaboration between surgeons, anaesthesiologists and surgical nurses.

    PMID:
    16924532
    [PubMed - indexed for MEDLINE]

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