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J Alzheimers Dis. 2006;9(3 Suppl):171-5.

Tau protein, the main component of paired helical filaments.

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  • 1Centro de Biología Molecular Severo Ochoa (CSIC-UAM). Facultad de Ciencias, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 - Madrid. Spain. javila@cbm.uam.es

Abstract

In this volume we commemorate the centennial of Alois Alzheimer's discovery of what was later known as Alzheimer's disease, named by Alzheimer's mentor, Emil Kraepelin. In a much more low level, our group remember in this issue a paper published twenty years ago. In that paper it was described that tau can self-polymerize and, at that time, it suggested that tau was not only a component of Alzheimer paired helical filaments, as indicated some months earlier during that year, 1986, but that it was the main component of Alzheimer paired helical filaments.

PMID:
16914856
[PubMed - indexed for MEDLINE]
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