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PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.
The Blood Center of Southeastern Wisconsin, Milwaukee 53233.
An antibody to a platelet integral membrane glycoprotein was found to cross-react with the previously identified CD31 myelomonocytic differentiation antigen and with hec7, an endothelial cell protein that is enriched at intercellular junctions. This antibody identified a complementary DNA clone from an endothelial cell library. The 130-kilodalton translated sequence contained six extracellular immunoglobulin (Ig)-like domains and was most similar to the cell adhesion molecule (CAM) subgroup of the Ig superfamily. This is the only known member of the CAM family on platelets. Its cell surface distribution suggests participation in cellular recognition events.
PMID: 1690453 [PubMed - indexed for MEDLINE]
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Cited by 89 PubMed Central articles
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O2 level controls hematopoietic circulating progenitor cells differentiation into endothelial or smooth muscle cells.
Berthelemy N, Kerdjoudj H, Schaaf P, Prin-Mathieu C, Lacolley P, Stoltz JF, Voegel JC, Menu P.
PLoS One. 2009; 4(5):e5514. Epub 2009 May 13.
[PLoS One. 2009]
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ReviewEndothelial signaling in paracellular and transcellular leukocyte transmigration.
Wittchen ES.
Front Biosci. 2009 Jan 1; 14:2522-45. Epub 2009 Jan 1.
[Front Biosci. 2009]
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A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.
Fox MA, Ho MS, Smyth N, Sanes JR.
Neural Dev. 2008 Sep 25; 3:24. Epub 2008 Sep 25.
[Neural Dev. 2008]
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