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J Occup Environ Med. 2006 Aug;48(8):759-70.

Community exposure to perfluorooctanoate: relationships between serum concentrations and exposure sources.

Author information

  • 1University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104-4284, USA. emmetted@mail.med.upenn.edu

Abstract

OBJECTIVE:

The objective of this study was to determine serum (perfluorooctanoate [PFOA]) in residents near a fluoropolymer production facility: the contributions from air, water, and occupational exposures, personal and dietary habits, and relationships to age and gender.

METHODS:

The authors conducted questionnaire and serum PFOA measurements in a stratified random sample and volunteers residing in locations with the same residential water supply but with higher and lower potential air PFOA exposure.

RESULTS:

Serum (PFOA) greatly exceeded general population medians. Occupational exposure from production processes using PFOA and residential water had additive effects; no other occupations contributed. Serum (PFOA) depended on the source of residential drinking water, and not potential air exposure. For public water users, the best-fit model included age, tap water drinks per day, servings of home-grown fruit and vegetables, and carbon filter use.

CONCLUSIONS:

Residential water source was the primary determinant of serum (PFOA).

PMID:
16902368
[PubMed - indexed for MEDLINE]
PMCID:
PMC3038253
Free PMC Article

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