Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA.
Cathepsins are proteases that were originally identified in the lysosome, where they participate in house keeping tasks such as degradation of phagocytosed photoreceptors. More recently, cathepsins have been detected outside of the lysosome, and associated with numerous diseases (keratoconus, retinal detachment, age related macular degeneration, and glaucoma). The most likely mechanism by which cathepsins contribute to ocular pathologies is via degradation of the extracellular matrix, and/or regulation of angiogenesis.
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on