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    Dev Cell. 2006 Aug;11(2):138-9.

    Canonical Wnt signaling: an unexpected new player.

    Habas R.

    Department of Biochemistry, UMDNJ-Robert Wood Johnson Medical School and The Cancer Institute of New Jersey, Piscataway, New Jersey 08854, USA.

    Canonical Wnt signaling, below the Fz/LRP receptor complex, induces the stabilization of beta-catenin via an unresolved mechanism. A recent study in Genes & Development introduces a new player and deepens our understanding of this signaling relay that plays pivotal roles during embryogenesis and tumorigenesis.

    PMID: 16890154 [PubMed - indexed for MEDLINE]

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