Non-odontogenic cysts are rare. Today, only 2 of the 18 non-odontogenic cysts that were described in 1982 are still classified as such: the nasopalatine duct cyst and the nasolabial cyst. The others are now classified in other groups. In the general practice the nasopalatine duct cyst is mostly seen as a swelling of the palate, just behind the central incisors. The nasolabial cyst is more rare and can be characterized as a paranasal swelling. Treatment of both cysts consists of surgical removal by intraoral approach. It is advisable to refer all cases of suspected non-odontogenic cysts, with the exception of the mucosal antral cyst, to an oral and maxillofacial surgeon in order to have the diagnosis confirmed.