Res Immunol. 1991 Sep;142(7):541-50.

A role for CD8+ T lymphocytes in the pathogenesis of AIDS.

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Laboratoire d'Immunobiologie, Faculté de Médecine, Paris V.

Abstract

Experimental and clinical evidence is presented which supports the hypothesis that CD8+ T lymphocytes aimed at suppressing HIV replication in infected CD4+ T cells may have an important role in the pathogenesis of AIDS by directly causing a decrease in CD4+ T lymphocyte numbers. Possible models to test this hypothesis are discussed.

PMID:: 1687487; [PubMed - indexed for MEDLINE]

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Review

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Antigens, CD8

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Cited by 1 PubMed Central article

Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group. [Clin Diagn Lab Immunol. 1995]
Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group.
Landay AL, Brambilla D, Pitt J, Hillyer G, Golenbock D, Moye J, Landesman S, Kagan J. Clin Diagn Lab Immunol. 1995 Jul; 2(4):462-8.

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A role for CD8+ T lymphocytes in the pathogenesis of AIDS.

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Abstract

Publication Types, MeSH Terms, Substances

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Supplemental Content

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Cited by 1 PubMed Central article

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