Format

Send to

Choose Destination
See comment in PubMed Commons below
Nephrol Dial Transplant. 2006 Nov;21(11):3211-4. Epub 2006 Jul 22.

Effects of L-carnitine infusions on inflammatory and nutritional markers in haemodialysis patients.

Author information

  • 1Dialysis Unit, Clinical Biochemistry Laboratory, Ankara Hospital, Ministry of Health, Turkey.

Abstract

BACKGROUND:

Carnitine loss through dialysis membranes is shown to be related to the lack of carnitine in long-term haemodialysis patients. It has been previously reported that haemodialysis patients might have benefited from carnitine supplementation.

METHODS:

A total of 21 chronic haemodialysis patients maintaining carnitine supplementation and 21 controls (haemodialysis patients not receiving carnitine) were included in the study. L-carnitine was used intravenously three times a week after each haemodialysis session, at a 20 mg/kg dose. C-reactive protein (CRP), lipid profile, transferrin, total protein and albumin levels were determined at baseline after 3 and 6 months of treatment, and compared with the control group.

RESULTS:

CRP levels were significantly decreased in carnitine group in contrast to the increase in the control group. Transferrin, total protein and albumin levels and body mass index (BMI) of the patients rose in the carnitine group.

CONCLUSIONS:

There was a significant benefit of L-carnitine on CRP, transferrin, total protein and albumin levels of the haemodialysis patients.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk