J Toxicol Clin Toxicol. 1991;29(4):543-51.

Acute sulfasalazine overdose.

Source

Department of Medicine (Gastroenterology), Michigan State University, East Lansing.

Abstract

Sulfasalazine (salicylazosulfapyridine, Azulfidine) has been widely used over the last half century for inflammatory bowel diseases, but overdose has not been reported. A 23 year-old male ingested 25 g of sulfasalazine in a suicide attempt. He underwent prompt treatment and survived with no ill-effects.

PMID:: 1684211; [PubMed - indexed for MEDLINE]

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Sulfasalazine

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Related citations in PubMed

Impaired folic acid absorption in inflammatory bowel disease: effects of salicylazosulfapyridine (Azulfidine). [Gastroenterology. 1973]
Impaired folic acid absorption in inflammatory bowel disease: effects of salicylazosulfapyridine (Azulfidine).
Franklin JL, Rosenberg HH. Gastroenterology. 1973 Apr; 64(4):517-25.
Massive sulfasalazine and paracetamol ingestion causing acidosis, hyperglycemia, coagulopathy, and methemoglobinemia. [J Toxicol Clin Toxicol. 1998]
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Dunn RJ. J Toxicol Clin Toxicol. 1998; 36(3):239-42.
Favorable effects of sulfasalazine on small bowel Crohn's disease: a long-term study. [Am J Gastroenterol. 1987]
Favorable effects of sulfasalazine on small bowel Crohn's disease: a long-term study.
Goldstein F, Farquhar S, Thornton JJ, Abramson J. Am J Gastroenterol. 1987 Sep; 82(9):848-53.
Review Sulfasalazine therapy in inflammatory bowel disease. [Gastroenterol Clin North Am. 1...]
Review Sulfasalazine therapy in inflammatory bowel disease.
Das KM. Gastroenterol Clin North Am. 1989 Mar; 18(1):1-20.
Review Drug therapy of inflammatory bowel disease. [Pharmacotherapy. 1983]
Review Drug therapy of inflammatory bowel disease.
Sack DM, Peppercorn MA. Pharmacotherapy. 1983 May-Jun; 3(3):158-76.

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